Priority: Palaven - No reason to avoid this one, as unlike several Priority quests, starting it doesn't instantly fail others.N7: Cerberus Lab - A small mission to give you more experience with the game's combat system.RELATED: Mass Effect: Things You May Not Know About The Krogan Genophage Optimal Mission Order: This section of the story focuses on Shepard trying to acquire the help of the Turians, Salarians, and Krogan. You have control of the Normandy and can go anywhere that's available. Therefore, if you want a playthrough that makes narrative sense and stops you from missing out on quests, then here's a guide.Īfter visiting the Citadel for the first time, the game begins to open up. For instance, if you've just heard about a colony under attack, then it doesn't make sense for Shepard to spend the next few hours roaming around the Citadel. Mass Effect 3 is a story-heavy game, and the order you do missions can positively or negatively impact the flow of the narrative. RELATED: Mass Effect Legendary Collection: Early Game Tips For Those Starting Mass Effect 3

After all, several missions are time or progression-sensitive, so those are easy to fail if you're not careful. However, there are some risks to embarking on some adventures at the wrong time. You need to do nearly all of the Priority quests in a set sequence, but you have more control over when you play each secondary operation. Despite not being as open as its predecessor, Mass Effect 3 gives you plenty of freedom regarding mission order.

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